SEARCH published: No CV benefit on reducing homocysteine

From www.theheart.org

June 22, 2010 | Sue Hughes

Oxford, UK – Substantial long-term reductions in blood homocysteine levels with folic-acid and vitamin-B12 supplementation did not have beneficial effects on vascular outcomes in the large-scale SEARCH trial [1]. But a silver lining of good news from the trial is that the vitamin supplements were not associated with any increase in cancer risk, which had been suggested in a previous study.

The trial, published in the June 23, 2010 issue of the Journal of the American Medical Association, was conducted by a team led by Dr Jane M Armitage (University of Oxford, UK).

Results from SEARCH were first reported by heartwire at the 2008 AHA meeting.

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